Alchemist

The Alchemist is an important craftsperson you will use from the start of the game up to and during the end game.

Which Services Do Alchemists Provide?

• Craft Elixirs and Incense
• Transmute materials into other materials
• Craft Lair Boss Keys

How Do I Craft Elixirs?

Elixirs are a great way to boost stats and increase the rate at which you earn experience points.

Many of them are crafted by an Alchemist and will require you to collect Crafting Materials out in the world from bushes and slaying monsters. They can also drop as rewards and some can be purchased from the Dark Citadel Vendor.

• Can have 1 Elixir active at the same time.
• Last 30 minutes and persist through death.
• Most affect only you.
• Can consume Elixirs whilst Crowd Controlled.
• You can have up to 3 Incense active at the same time.
• Buffs from both your Elixir and Incense can stack but the Experience buff from any Elixir you have active will only stack with the Experience buff from a single Incense.
• Most can be traded with other players.
• Full list of Elixirs, including those the Alchemist can not craft.

Expand to see a list of all the Elixirs the Alchemist can craft for you. ↓

Elixir Lvl Description Cost Elixir of Advantage 10 Increases Attack Speed by 7% and Lucky Hit by 7%. Experience gained increased by 5% for 30 minutes. 5 Bundled Herbs 1,000 Gold Elixir of Advantage II 50 Increases Attack Speed by 15% and Lucky Hit by 15%. Experience gained increased by 8% for 30 minutes. 10 Bundled Herbs 10 Angelbreath 2,000 Gold Elixir of Cold Resistance 40 Increases Cold Resistance by + 5%. Experience gained is increased by 5%. 20 Bundled Herbs 300 Sapphire Fragment 3,000 Gold Elixir of Cold Resistance II 50 Increases Cold Resistance by + 15%. Experience gained increased by 8%. 10 Bundled Herbs 10 Angelbreath 300 Sapphire Fragment 2,000 Gold Elixir of Destruction 10 Increases Overpower damage by 7% and Vulnerable damage by 7%. Experience gained increased by 5% for 30 minutes. 5 Bundled Herbs 1,000 Gold Elixir of Destruction II 50 Increases Overpower damage by 15% and Vulnerable damage by 15%. Experience gained increased by 8% for 30 minutes. 10 Bundled Herbs 10 Angelbreath 2,000 Gold Elixir of Fire Resistance 40 Increases Fire Resistance by + 5%. Experience gained increased by 5%. 20 Bundled Herbs 300 Ruby Fragment 3,000 Gold Elixir of Fire Resistance II 50 Increases Fire Resistance by + 15%. Experience gained increased by 8%. 40 Bundled Herbs 30 Angelbreath 300 Ruby Fragment 6,000 Gold Elixir of Fortitude 20 Increases Maximum Life by 5% and Experience gained by 5% for 30 minutes. 10 Bundled Herbs 200 Skull Fragment 2,000 Gold Elixir of Fortitude II 50 Increases Maximum Life by 10% and Experience gained by 8% for 30 minutes. 20 Bundled Herbs 20 Angelbreath 200 Skull Fragment 4,000 Gold Elixir of Hollow Unmaking 35 Increases damage to Hollows and Hollow-infected monsters by 10%. Experience gained increased by 8%. 50 Bundled Herbs 35 Angelbreath 150 Emerald Fragment 1,000 Gold Iron Barb Elixir 20 Increases Armor by + 250 and Thorns by 150. Experience gained is increased by 5% for 30 minutes. 10 Bundled Herbs 100 Diamond Fragment 2,000 Gold Iron Barb Elixir II 50 Increases Armor by + 500 and Thorns by 250. Experience gained is increased by 8% for 30 minutes. 20 Bundled Herbs 20 Angelbreath 200 Diamond Fragment 4,000 Gold Elixir of Lightning Resistance 40 Increases Lightning Resistance by + 5%. Experience gained increased by 5%. 20 Bundled Herbs 300 Topaz Fragment 3,000 Gold Elixir of Lightning Resistance II 50 Increases Lightning Resistance by + 15%. Experience gained increased by 8%. 40 Bundled Herbs 30 Angelbreath 300 Topaz Fragment 6,000 Gold Elixir of Poison Resistance 40 Increases Poison Resistance by + 5%. Experience gained increased by 5%. 20 Bundled Herbs 300 Emerald Fragment 3,000 Gold Elixir of Poison Resistance II 50 Increases Poison Resistance by + 15%. Experience gained increased by 8%. 40 Bundled Herbs 30 Angelbreath 300 Emerald Fragment 6,000 Gold Elixir of Precision 10 Increases Critical Strike Chance by 4% and Critical Strike Damage by 25%, and Experience by 5% for 30 minutes. 5 Bundled Herbs 1,000 Gold Elixir of Precision II 50 Increases Critical Strike Chance by 6% and Critical Strike Damage by 35%, and Experience by 8% for 30 minutes. 10 Bundled Herbs 10 Angelbreath 2,000 Gold Elixir of Resourcefulness 20 Grants 10% Resource Cost Reduction and 10 Maximum Resource. Experience gained is increased by 5% for 30 minutes. 20 Bundled Herbs 2000 Gold Elixir of Resourcefulness II 50 Grants 20%, Resource Cost Reduction and 25% Maximum Resource. Experience gained increased by 8% for 30 minutes. 10 Bundled Herbs 10 Angelbreath 2,000 Gold Elixir of Shadow Resistance 40 Increases Shadow Resistance by + 5%. Experience gained increased by 5%. 20 Bundled Herbs 300 Amethyst Fragment 3,000 Gold Elixir of Shadow Resistance II 50 Increases Shadow Resistance by + 15%. Experience gained increased by 8%. 40 Bundled Herbs 30 Angelbreath 300 Amethyst Fragment 6,000 Gold

• See all Elixirs (crafted, bought and found)

How Do I Craft Incense?

Incense are a great way to boost stats and increase the rate at which you earn experience points.

Many of them are crafted by an Alchemist and will require you to collect Crafting Materials out in the world from bushes and slaying monsters. Some can be purchased from the Dark Citadel Vendor.

• Can have 1 Incense from each of the 3 categories active at the same time
• They last 30 minutes and persist through death
• They affect you and nearby players (grouped or ungrouped)
• Buffs stack with any Elixir you have active and Incense burned by other nearby players (grouped or ungrouped)
• The 5% Experience bonus from Incense doesn’t stack with bonuses from other Incense, whether used by you or nearby players. However, it does stack with the Experience bonus granted by an active Elixir.
• Some can be traded with with other players.
• Full list of Incense including those the Alchemist can not create.

There are 3 categories of Incense:

• Core Stat Incense
• Defensive Incense
• Resistance Incense

• The Incense bought from the Vendor in the Dark Citadel only last for 20 minutes and are not crafted but purchased with Citadel Coins

+ Expand to see a list of all the Incense the Alchemist can craft for you.↓

Incense Type Req Lvl Description Cost Ancient Times Core 50 Increases Strength by 100 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 60 Bundled Herbs 2 Veiled Crystal 35 Ruby Fragment 2,500 Gold Blessed Guide Core 50 Increases Willpower by 100 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 60 Bundled Herbs 2 Veiled Crystal 35 Amethyst Fragment 2,000 Gold Queen's Supreme Core 50 Increases Dexterity by 100 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 60 Bundled Herbs 2 Veiled Crystal 35 Emerald Fragment 2,000 Gold Sage's Whisper Core 50 Increases Intelligence by 100 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 60 Bundled Herbs 2 Veiled Crystal 35 Topaz Fragment 2,000 Gold Spiral Morning Core 50 Increases All Stats by 60 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 80 Bundled Herbs 6 Angelbreath 6 Veiled Crystal 3,500 Gold Reddamine Buzz Defensive 60 Increases Maximum Life by 750 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 75 Bundled Herbs 5 Angelbreath 4 Veiled Crystal 140 Ruby Fragment 3,000 Gold Scents of the Desert Afternoon Defensive 50 Increases Thorns by 400 for all nearby players and increases Experience by 5%. Lasts 30 minutes. 80 Bundled Herbs 7 Angelbreath 6 Veiled Crystal 160 Emerald Fragment 4,000 Gold Spirit Dance Defensive 50 Increases chance to Dodge by 5% for all nearby players and increases Experience by 5%. Lasts 30 minutes. 90 Bundled Herbs 9 Angelbreath 9 Veiled Crystal 5,000 Gold Song of the Mountain Defensive 45 Increases Armor by + 10% for all nearby players and increases Experience by 5%. Lasts 30 minutes. 55 Bundled Herbs 1 Veiled Crystal 30 Skull Fragment 1,500 Gold Desert Escape Resistance 55 Increases Fire, Cold and Shadow Resistances by + 7% for all nearby players and increases Experience by 5%. Lasts 30 minutes. 70 Bundled Herbs 4 Angelbreath 3 Veiled Crystal 50 Amethyst Fragment 50 Sapphire Fragment 2,500 Gold Storm of the Wilds Resistance 55 Increases Lightning,Cold and Poison Resistances by + 7% for all nearby players and increases Experience by 5%. Lasts 30 minutes. 65 Bundled Herbs 4 Angelbreath 3 Veiled Crystal 50 Emerald Fragment 50 Topaz Fragment 2,500 Gold Soothing Spices Resistance 50 Increases Resistance to All Elements by + 5%, and Armor by + 5% for all nearby players and increases Experience by 5%. Lasts 30 minutes. 85 Bundled Herbs 8 Angelbreath 7 Veiled Crystal 85 Diamond Fragment 85 Skull Fragment 4,500 Gold

How Do I Craft Materials?

These are things the Alchemist can craft that can be used for upgrading items at Blacksmith's, Occultist's and Jeweler's.

+ Expand to see a list of Crafting Materials the Alchemist can craft for you.↓

Material Quality Description Found In Cost to Craft Obducite I & II Rare Used in Masterworking at the Blacksmith to upgrade an item. 3 Obducite can also be crafted at the Alchemist. Nightmare Dungeons Infernal Hordes Undercity in Kurast Obducite I 1 x Ingolith Obducite II 1 x Neathiron Veiled Crystal Rare Veiled Crystals are used by the Alchemist to craft Incense and refine materials, at the Blacksmith to upgrade gear, at the Occultist to Enchant and the Jeweler to add sockets to items. Salvaging Rare, Legendary and Unique equipment at the Blacksmith. Cache rewards from the Tree of Whispers Legion Events Infernal Hordes Elite Monsters x 10 11 Rawhide 100 Iron Chunk 25,000 Gold Abstruse Sigil Legendary Abstruse Sigils are used by the Blacksmith to improve Legendary Jewlery at the Blacksmith and Jeweler. Fragments from storied relics and talismans with truly unusual properties. Salvaging Legendary, Unique and Mythic Jewelry at the Blacksmith. Cache rewards from the Tree of Whispers. x 10 100 Veiled Crystals 50,000 Gold Baleful Fragment Legendary Baleful Fragments are used by the Blacksmith to improve Legendary Jewlery at the Blacksmith and Jeweler. Shards from storied weapons with truly unusual properties Salvaging Legendary, Unique and Mythic Jewelry at the Blacksmith. Cache rewards from the Tree of Whispers. x 10 100 Veiled Crystals 50,000 Gold Forgotten Soul Legendary Forgotten Souls are used by the Blacksmith and Occultist to improve Ancestral Legendary items. Is it a stone, an organ, or something else? Indescribably, it is all of those things. Salvaging Ancestral Legendary items at the Blacksmith. Legion Events Tortured Gift Chests in Helltides Infernal Hordes Undercity in Kurast Cache rewards from the Tree of Whispers x 10 100 Veiled Crystals 500,000 Gold

How Do I Make Lair Keys?

Lair Boss Keys are items needed to open the Lair Boss Hoard (Loot Chest) after defeating the Lair Boss. They are not physical keys but simply a consumable item required to access the hoard’s rewards.

• Lair Boss Keys drop in End Game activities such as Helltides, Nightmare Dungeons, Whispers, World Bosses and Legion Events.
• They can be crafted at the Alchemist.
• If in a group each player needs their own Key.
• Stack up to 100.

+ Expand to see a list of the Lair Boss Keys Alchemist can craft for you.↓

Item Quality Description Found In Cost to Craft Abhorrent Heart Lair Boss Key Abhorrent Heart is an item used to open The Harbinger of Hatred's Hoard (Reward Chest) in the Harbinger's Den in Nahantu (Map). The Harbinger of Hatred can be target-farmed for its Unique and Mythic Loot. Commonly from Lair Boss Hoards in: Fields of Judgement (Urivar) (Map) Sometimes from: World Bosses Undercity in Kurast with Tribute of Titans Only in Torment Difficulty 1 Stygian Stone or 4 Khazra Horn 8 Judicator's Masks Pincushioned Doll Lair Boss Key Pincushioned Doll is an item used to open Andariel's Hoard (Reward Chest) in The Hanged Man's Hall (Map). Andariel can be target-farmed for her Unique and Mythic Loot. Commonly from Lair Boss Hoards in: Glacial Fissure (The Beast in the Ice) (Map) Ancient's Seat (Lord Zir) (Map) Sometimes from: World Bosses Undercity in Kurast with Tribute of Titans Only in Torment Difficulty 1 Stygian Stone Shard of Agony Lair Boss Key Shard of Agony is an item used to open Duriel's Hoard (Reward Chest) in the Gaping Crevasse in Kehjistan (Map). Duriel can be target-farmed for her Unique and Mythic Loot. Commonly from Lair Boss Hoards in: Hall of the Penitent (Grigoire) (Map) Malignant Burrow (Vashan) (Map) Sometimes from: World Bosses Undercity in Kurast with Tribute of Titans Only in Torment Difficulty 1 Stygian Stone Exquisite Blood Lair Boss Key / Crafting Exquisite Blood is a Lair Boss Key used to open Lord Zir 's Hoard (Reward Chest) in the Ancient's Seat in the Darkened Way (Map). It is also used to craft a Pincushioned Doll which is a Lair Boss Key required to access Andariel's Hoard. Commonly from: World Bosses Legion Events Blood Maiden in Helltides Undercity in Kurast with Tribute of Titans (Map) Sometimes from: Tree of Whispers Caches Mercenary Bartering Only in Torment Difficulty Distilled Fear Lair Boss Key / Crafting Distilled Fear is a Lair Boss Key used to open The Beast in the Ice's Hoard (Reward Chest) in The Glacial Fissure in the Desolate Highlands (Map). It is also used to craft a Pincushioned Doll which is a Lair Boss Key required to access Andariel's Hoard. Commonly from: Nightmare Dungeons Undercity in Kurast with Tribute of Titans (Map) Sometimes from: Tree of Whispers Caches World Bosses Mercenary Bartering Only in Torment Difficulty Living Steel Lair Boss Key / Crafting Living Steel is a Lair Boss Key used to open Grigoire's Hoard (Reward Chest) in the Hall of the Penitent (Map) in the Dry Steppes. It is also used to craft a Shard of Agony which is a Lair Boss Key required to access Duriel's Hoard. Commonly from: Helltides Undercity in Kurast with Tribute of Titans (Map) Sometimes from: Tree of Whispers Caches World Bosses Mercenary Bartering Only in Torment Difficulty Judicator's Mask Lair Boss Key / Crafting The Judicator's Mask is a Lair Boss Key used to open Urivar's Hoard (Reward Chest) in The Fields of Judgement (Map) in Nahantu. It is also used to craft a Abhorrent Heart which is a Lair Boss Key required to access the Harbinger of Hatred's Hoard. Sometimes from: Tree of Whispers Caches World Bosses Mercenary Bartering Only in Torment Difficulty Malignant Heart Lair Boss Key / Crafting The Malignant Heart is a Lair Boss Key used to open Varshan's Hoard (Reward Chest) in The Malignant Burrow (Map) beneath the Tree of Whispers in Hawezar. It is also used to craft a Shard of Agony which is a Lair Boss Key required to access Duriel's Hoard. Commonly from: Tree of Whispers Caches Undercity in Kurast with Tribute of Titans (Map) Sometimes from: World Bosses Mercenary Bartering Only in Torment Difficulty

Where Do I Find Alchemists?

Alchemists are found in the following locations:

Scosglen

• Cerrigar - ([Map])
• Tur Dulra - ([Map])

Dry Steppes

• Ked Bardu - ([Map])

Fractured Peaks

• Kyovoshad - ([Map])

Hawezar

• Tree of Whispers - ([Map])
• Wejinhani - ([Map])
• Zarbinet - ([Map])

Kehjistan

• Gea Kul - ([Map])

Nahantu

• Kurast Docks - ([Map])
• Kurast Bazaar - ([Map])

Changes to Alchemist

Since Diablo 4's release, the Alchemist has seen a few changes to the services they offer and these are detailed below.

+ Expand to see Patch Changes to the Alchemist.↓

Patch 2.5.0, ETA December 2025 The Alchemist ability to upgrade Healing Potions has been removed from the game. Old details have been archived. Incense recategorised into 3 categories, Core, Defensive and Resistance. Stats increased on all. Patch 2.3.0, July 1, 2025 Added a transmutation recipe for exchanging the Judicator's Mask into Abhorrent Hearts at the Alchemist. Patch 2.1.0, January 21, 2025 Chorus of War Incense removed. Many Incense received a stat bonus. Patch 2.0.1, October 8 2024 Incense now categorised into Core, Defensive and Resistance. Patch 1.5.0, August 6, 2024 Can now consume elixirs when Crowd Controlled. Patch 1.4.3, June 17, 2024 Minor Healing Potion - Initial healing increased by 50%. Light, and Moderate Healing Potions - Initial healing increased by 100%. Strong, Greater, Major, and Superior Healing Potions - Initial healing increased by 200%. Patch 1.4.0, May 14, 2024 Elixirs Complete reworking of Elixirs with some removed, others combined and adding some new ones including rare. Resource Upgrades Removed Gallowine, Blightshade, Biteberry, Lifesbane, Howler Moss and Reddamine. Replaced with Bundled Herbs that do not need upgrading. Removed Silver Ore and Superior Leather. Transmute Added Tyrael's Might Reduced level requirement from 60 to 35 Patch 1.3.2, February 13, 2024 Uber Unique Items can now be salvaged to provide a new resource, Resplendent Sparks. Players can bring 5 Resplendent Sparks to the Alchemist and Transmute an Uber Unique of their choice. The Refine Resources tab at the Alchemist has been renamed Transmute, and the option to craft an Uber Unique item can be found under that tab. Note that the preview window for crafting an Uber Unique won't display the item’s affixes.