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Alchemist

From Diablo 4 Wiki

The Alchemist is an important craftsperson you will use from the start of the game up to and during the end game.

Which Services the Alchemist Provides

  • Upgrade your health potions as you level up your character
  • Craft Elixirs and Incense
  • Transmute body parts to summon Varshan who can be farmed for particular unique items
  • Transmute Resplendent Sparks to create a handful of different Uber Uniques
Health Potion

Health Potion Upgrades

You do not craft health potions, they are collected as loot. However, how much health they give you when you drink them depends on what level you have upgraded them to at the Alchemist.

At different Player Levels in the game, you can visit the Alchemist to upgrade your health potion level. This will cost you some gathered herbs and gold.


+ Expand to see the upgrade to health potions the Alchemist can perform for you.
Potion Req Lvl Description Cost
Weak Healing Vial 1 Heals 17 Life instantly and 35% Life over 3 seconds. -
Tiny Healing Vial 10 Heals 48 Life instantly and 35% Life over 3 seconds.

10 Bundled Herbs
5,000 Gold

Minor Healing Vial 20 Heals 120 Life instantly and 35% Life over 3 seconds.

15 Bundled Herbs
10,000 Gold

Light Healing Vial 30 Heals 282 Life instantly and 35% Life over 3 seconds.

245 Bundled Herbs
150,000 Gold

Moderate Healing Vial 45 Heals 510 Life instantly and 35% Life over 3 seconds.

70 Bundled Herbs
500,000 Gold

Strong Healing Vial 60 Heals 1,133 Life instantly and 35% Life over 3 seconds.

110 Bundled Herbs
15 Angelbreath
1,000,000 Gold

Greater Healing Vial 70 Heals 1,677 Life instantly and 35% Life over 3 seconds.

180 Bundled Herbs
20 Angelbreath
5 Forgotten Soul
3,000,000 Gold

Major Healing Vial 80 Heals 2,482 Life instantly and 35% Life over 3 seconds.

290 Bundled Herbs
25 Angelbreath
10 Forgotten Soul
5,000,000 Gold

Superior Healing Vial 90 Heals 3,821 Life instantly and 35% Life over 3 seconds.

425 Bundled Herbs
30 Angelbreath
20 Forgotten Soul
7,000,000 Gold


Elixir of Poison

Elixir Crafting

You can have one Elixir active at a time. Drinking another elixir will replace the existing elixir. They only buff you and not your party members. You can however trade Elixirs.

Elixirs increase your statistics or buffs and also increase the rate at which you earn experience points by 5% - 8% and last at most 30 minutes. The effects of the Elixir persist after death.

They are crafted mostly from plants that you can gather but also other Crafting Materials such as Veiled Crystal and gem fragments.

Elixirs you can craft and some that you can't (listed here) will also drop as rewards from caches and Helltide chests and they are automatically stacked in your inventory. You can trade them with other players.

Quick Menu


+ Expand to see a list of all the Elixirs the Alchemist can craft for you.
Elixir Lvl Description Cost
Elixir of Advantage 10 Increases Attack Speed by 7% and Lucky Hit by 7%. Experience gained increased by 5%. 5 Bundled Herbs
1,000 Gold
Elixir of Advantage II 50 Increases Attack Speed by 15% and Lucky Hit by 15%. Experience gained increased by 8%. 10 Bundled Herbs
10 Angelbreath
2,000 Gold
Elixir of Cold Resistance 40 Increased Cold Resistance increased by + 20% and Maximum Cold Resistance increased by 4%. Experience gained increased by 5%. 20 Bundled Herbs
300 Sapphire Fragment
3,000 Gold
Elixir of Cold Resistance II 50 Increases Cold Resistance by + 30%, Maximum Cold Resistance by 6%. Experience gained increased by 8%. 40 Bundled Herbs
30 Angelbreath
300 Sapphire Fragment
6,000 Gold
Elixir of Destruction 10 Increases Overpower damage by 7% and Vulnerable damage by 7%. Experience gained increased by 5%. 5 Bundled Herbs
1,000 Gold
Elixir of Destruction II 50 Increases Overpower damage by 15% and Vulnerable damage by 15%. Experience gained increased by 8%. 10 Bundled Herbs
10 Angelbreath
2,000 Gold
Elixir of Fire Resistance 40 Increases Fire Resistance by + 20% and Maximum Fire Resistance by 4%. Experience gained increased by 5%. 20 Bundled Herbs
30 Ruby Fragment
3,000 Gold
Elixir of Fire Resistance II 50 Increases Fire Resistance by + 30% and Maximum Fire Resistance by 6%. Experience gained increased by 8%. 40 Bundled Herbs
30 Angelbreath
300 Ruby Fragment
6,000 Gold
Elixir of Fortitude 20 Increases Maximum Life by 10% and Experience gained by 5% for 30 minutes. 10 Bundled Herbs
200 Skull Fragment
2,000 Gold
Elixir of Fortitude II 50 Increases Maximum Life by 20% and Experience gained by 8% for 30 minutes. 20 Bundled Herbs
20 Angelbreath
200 Skull Fragment
4,000 Gold
Elixir of Holy Bolts
Rare
Season icon.png Season 4 Only
10 After killing an enemy, Holy Bolts fire from the corpse of that enemy. Experience gained is increased by 6%. Lasts 15 minutes. 20 Bundled Herbs
300 Sapphire Fragment
3,000 Gold
Iron Barb Elixir 20 Increases Armor by + 300 and Thorns by 150. Experience gained is increased by 5% for 30 minutes. 10 Bundled Herbs
100 Diamond Fragment
2,000 Gold
Iron Barb Elixir II 50 Increases Armor by + 500 and Thorns by 250. Experience gained is increased by 8% for 30 minutes. 20 Bundled Herbs
20 Angelbreath
200 Diamond Fragment
4,000 Gold
Elixir of Lightning Resistance 40 Increases Lightning Resistance by + 20% and Maximum Lightning Resistance by 4%. Experience gained increased by 5%. 20 Bundled Herbs
300 Topaz Fragment
3,000 Gold
Elixir of Lightning Resistance II 50 Increases Lightning Resistance by + 30% and Maximum Lightning Resistance by 6%. Experience gained increased by 8%. 40 Bundled Herbs
30 Angelbreath
300 Topaz Fragment
6,000 Gold
Elixir of Momentum
Rare
Season icon.png Season 4 Only
10 After killing an enemy, increase Movement Speed by 3% for 5 seconds, stacking up to 15 times. Experience gained is increased by 6%. Lasts 15 minutes. 20 Bundled Herbs
300 Sapphire Fragment
3,000 Gold
Elixir of Poison Resistance 40 Increases Poison Resistance by + 20% and Maximum Poison Resistance by 4%. Experience gained increased by 5%. 20 Bundled Herbs
300 Emerald Fragment
3,000 Gold
Elixir of Poison Resistance II 50 Increases Poison Resistance by + 30% and Maximum Poison Resistance by 6%. Experience gained increased by 8%. 40 Bundled Herbs
30 Angelbreath
300 Emerald Fragment
6,000 Gold
Elixir of Precision 10 Critical Strike Chance increased by 4%, Critical Strike Damage increased by 25%, and Experience by 5% for 30 minutes. 5 Bundled Herbs
1,000 Gold
Elixir of Precision II 50 Critical Strike Chance increased by 6%, Critical Strike Damage increased by 35%, and Experience by 8% for 30 minutes. 10 Bundled Herbs
2,000 Gold
Elixir of Resource 20 Resource cost reduced by 10%, Maximum Resource increased by 10. Experience gained increased by 5%. 20 Bundled Herbs
2,000 Gold
Elixir of Resource II 50 Resource cost reduced by 20%, Maximum Resource increased by 25. Experience gained increased by 8%. 10 Bundled Herbs
10 Angelbreath
2,000 Gold
Elixir of Shadow Resistance 40 Increases Shadow Resistance by + 20% and Maximum Shadow Resistance by 4%. Experience gained increased by 5%. 20 Bundled Herbs
300 Amethyst Fragment
3,000 Gold
Elixir of Shadow Resistance II 50 Increases Shadow Resistance by + 30% and Maximum Shadow Resistance by 6%. Experience gained increased by 8%. 40 Bundled Herbs
30 Angelbreath
300 Amethyst Fragment
6,000 Gold


Incense

Incense Crafting

Incense is a great way to boost stats and increase the rate at which you earn experience points.

You will need to collect Crafting Materials out in the world from bushes and slaying monsters. You take these materials to the Alchemist who can craft them into Incense. These processes will also cost you gold.

  • Can have 1 Incense from each of the 3 Types active at the same time
  • They last 20 minutes and persist through death
  • They affect you and nearby players (grouped or ungrouped)
  • Buffs stack with any Elixir you have active and Incense burned by other nearby players (grouped or ungrouped)
  • The Experience buff from your incense does not stack with the Experience buff from another incense burnt by yourself or other players. The Experience buff from any Elixir you have active will stack with a Experience buff from a single Incense.
  • They can be traded with other players


+ Expand to see a list of all the Incense the Alchemist can craft for you.
Incense Type Req Lvl Description Cost
Song of the Mountain 1 45 Increases Armor by + 200 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 55 Bundled Herbs
1 Veiled Crystal
30 Skull Fragment
1,500 Gold
Ancient Times 1 50 Increases Strength by 25 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 60 Bundled Herbs
2 Veiled Crystal
35 Ruby Fragment
2,500 Gold
Blessed Guide 1 50 Increases Willpower by 25 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 60 Bundled Herbs
2 Veiled Crystal
35 Amethyst Fragment
2,000 Gold
Queen's Supreme 1 50 Increases Dexterity by 25 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 60 Bundled Herbs
2 Veiled Crystal
35 Emerald Fragment
2,000 Gold
Sage's Whisper 1 50 Increases Intelligence by 25 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 60 Bundled Herbs
2 Veiled Crystal
35 Topaz Fragment
2,000 Gold
Desert Escape 1 55 Increases Fire, Cold and Shadow Resistances by + 15%, and their Maximum Resistances by + 2% for all nearby players and increases Experience by 5%. Lasts 20 minutes. 70 Bundled Herbs
4 Angelbreath
3 Veiled Crystal
50 Amethyst Fragment
50 Sapphire Fragment
2,500 Gold
Storm of the Wilds 1 55 Increases Lightning,Cold and Poison Resistances by + 15% and their Maximum Resistance by + 2% for all nearby players and increases Experience by 5%. Lasts 20 minutes. 65 Bundled Herbs
4 Angelbreath
3 Veiled Crystal
50 Emerald Fragment
50 Topaz Fragment
2,500 Gold
Reddamine Buzz 2 60 Increases Maximum Life by 500 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 75 Bundled Herbs
5 Angelbreath
4 Veiled Crystal
140 Ruby Fragment
3,000 Gold
Spiral Morning 2 65 Increases All Stats by 15 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 80 Bundled Herbs
6 Angelbreath
6 Veiled Crystal
3,500 Gold
Scents of the Desert Afternoon 2 70 Increases Thorns by 250 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 80 Bundled Herbs
7 Angelbreath
6 Veiled Crystal
160 Emerald Fragment
4,000 Gold
Soothing Spices 2 75 Increases Resistance to All Elements by + 10%, Maximum Resistance to All Elements by + 1%, and Armor by + 150 for all nearby players and increases Experience by 5%. Lasts 20 minutes. 85 Bundled Herbs
8 Angelbreath
7 Veiled Crystal
85 Diamond Fragment
85 Skull Fragment
4,500 Gold
Spirit Dance 1 80 Increases chance to Dodge by 5% for all nearby players and increases Experience by 5%. Lasts 20 minutes. 90 Bundled Herbs
9 Angelbreath
9 Veiled Crystal
5,000 Gold
The Creatures of Night 3 N/A Increases the damage of Hit Effects by 100% for all nearby players and increases Experience by 5%. Lasts 20 minutes. N/A
Chorus of War 3 100 Increases All Stats by 40 and Critical Strike and Overpower damage by 5% for every nearby player and increases Experience by 5%. Lasts 20 minutes. 100 Bundled Herbs
10 Angelbreath
10 Veiled Crystal
100 Ruby Fragment
100 Sapphire Fragment

6,000 Gold


Crafting Material

Crafting Materials

These are things the Alchemist can craft that can be used for other crafting.

+ Expand to see a list of Crafting Materials the Alchemist can craft for you.
Material Quality Description Cost to Craft
Obducite Cache

Obducite Cache
Magic A Cache crafted by the Alchemist that contains 5 Obducites to be used during Masterworking ranks 1 to 4 at the Blacksmith. 1 x Ingolith
200 Gold


Ingolith Cache

Ingolith Cache
Rare A Cache crafted by the Alchemist that contains 5 Ingolith to be used during Masterworking ranks 5 to 8 at the Blacksmith. 1 x Neathiron
600 Gold


Summoning Items Gurgling Head

Summoning Items

There are quite a few Summoning Items in Diablo 4 and the Alchemist is involved in just a few of them, detailed below. Read the Summoning Items page for all items associated with summoning members of the Boss Ladder and others.

One of each of these body parts is required to summon Varshan in the Malignant Burrow at the Tree of Whispers. You can find the body parts in Caches rewarded at the Tree of Whispers for completing Whispers_of_the_Dead but the Alchemist can also craft them for you.

If you have lots of one particular body part you can use them at the Alchemist to craft a different random part in a Malignant Body Cache.

These materials must be in your bag, not your stash, for the Alchemist to use them.


+ Expand to see a list of Summoning Items the Alchemist can craft and refine for you.
Name Type Description Where to Find/Cost to Craft
Blackened Femur

Blackened Femur for Varshan
Summoning/Crafting
Assembled beneath the Tree of Whispers (Map) within the Malignant Burrow to summon the Echo of Varshan. A Whisper Caches and Legion Events. 1 Malignant Heart
4 Coiling Ward
15 Veiled Crystal
50,000 Gold
Gurgling Head

Gurgling Head for Varshan
Summoning/Crafting
Assembled beneath the Tree of Whispers (Map) within the Malignant Burrow to summon the Echo of Varshan. Whisper Caches and Legion Events. 1 Malignant Heart
4 Abstruse Sigil
15 Veiled Crystal
50,000 Gold
Trembling Hand

Trembling Hand for Varshan
Summoning/Crafting
Assembled beneath the Tree of Whispers (Map) within the Malignant Burrow to summon the Echo of Varshan. Whisper Caches and Legion Events. 1 Malignant Heart
4 Baleful Fragment
15 Veiled Crystal
50,000 Gold
Name Type Description Cost to Craft
Malignant Body Cache

Malignant Body Cache for Varshan
Summoning
Contains either a Gurgling Head, Blackened Femur or Trembling Hand used for summoning The Echo of Varshan in the Malignant Burrow at the Tree of Whispers (Map). 1 Gurgling Head/Blackened Femur or
1 Trembling Hand
1 Abstruse Sigil/Baleful Fragment or
1 Coiling Ward
5 Veiled Crystal
20,000 Gold


Uber Unique Amulet Crafted

Transmute Resplendent Sparks

If you have been farming Uber Uniques from Duriel and Andariel that you do not need you can salvage them at the Blacksmith for Resplendent Sparks which can then be used at the Alchemist to craft into other Uber Uniques listed below.

Each recipe requires:

  • 4 Resplendent Sparks
  • 50,000,000 Gold
  • Requires Level 35


+ Expand to see a list of Uber Uniques the Alchemist can craft for you.
4138623405.png

Andariel's Visage

The horrific whispers of the Maiden of Anguish flicker through your mind, pushing you ever closer to madness...

Type: Mythic Unique Helm
Class: All Classes

Description: Lucky Hit: Up to a 20% chance to trigger a poison nova that applies 4,500 Poisoning damage over 5 seconds to enemies in the area.


    Affixes: (Item Power 925)
    • +18 All Stats
    • +10.0% Attack Speed
    • +2.0% Life Steal
    • +60.0% Poison Resistance
    595234048.png

    Ahavarion Spear of Lycander

    "The angel Lycander left us a portion of her power in this spear. It is all the proof I need that she watches over us still." - Oracle Argoysni

    Type: Mythic Unique Staff
    Class: Druid, Sorcerer

    Description: Gain a random Shrine effect for 20 seconds after killing an Elite enemy. Can only occur once every 30 seconds.

    • +40.0% Damage Over Time

    Affixes: (Item Power 925)
    • +16.0% Critical Strike Chance
    • +20.0% Attack Speed
    • +35.0% Damage
    • Lucky Hit: Up to a +28.0% Chance to Stun (CC) for 2 Seconds
    2397813516.png

    Doombringer

    Whenever this ancient sword has reappeared throughout history, it portends a time of great strife, as well as a devastating loss of life.

    Type: Mythic Unique Sword
    Class: Barbarian, Necromancer, Rogue

    Description: Lucky Hit: Up to a 25% chance to deal 900 Shadow damage to surrounding enemies and reduce their damage done by 20% for 5 seconds.


    Affixes: (Item Power 925)
    • +19.5% Core Damage
    • +17.5% Damage
    • Lucky Hit: Up to a 5% Chance to Heal +1,058 Life
    • 26.0% Maximum Life
    25610294.png

    Harlequin Crest

    "This headdress was once worn by an assassin disguised as a court mage. Her treachery was unveiled, but not before she used its magic to curse the king's entire lineage." - The Fall of House Aston

    Type: Ancestral Mythic Unique Helm
    Class: All Classes

    Description: Gain 20% Damage Reduction. In addition, gain +4 Ranks to all Skills.


      Affixes: (Item Power 925)
      • +1,528 Maximum Life
      • 7.0% Cooldown Reduction
      • 12.0% Resource Generation
      • +28 All Stats
      2952066822.png

      The Grandfather

      An unbroken lineage of unwavering strength.

      Type: Mythic Unique Two-Handed Sword
      Class: Barbarian, Necromancer

      Description: Increases your Critical Strike Damage by 100%[x]. The other properties on this weapon can roll higher than normal.

      • +35.0% Critical Strike Damage

      Affixes: (Item Power 925)
      • +56.0% Damage
      • +3,056 Maximum Life
      • +72 All Stats
      • Ignores Durability Loss
      2403703919.png

      Melted Heart of Selig

      "Do not allow your passions to become obsessions. Fuel the fire that burns within you, but it is madness to allow yourself to become ash to please an uncaring universe." - Last words of Master Selig

      Type: Mythic Unique Amulet
      Class: All Classes

      Description: Gain 60 Maximum Resource.When taking damage, 75% is drained as 2 Resource for every 1% of Maximum Life you would have lost.

      • +25.0% Resistance to All Elements

      Affixes: (Item Power 925)
      • +36 All Stats
      • +17.5% Movement Speed
      • +70.5% Damage while Healthy
      • 12.0% Resource Generation
      1903997083.png

      Ring of Starless Skies

      "Yours is the power to pluck the stars from the heavens with the ease of a child gathering fruit from the bough." - Unknown

      Type: Mythic Unique Ring
      Class: All Classes

      Description: Spending your Primary Resource reduces the Resource cost of your Skills and increases your damage by 10%[x] for 3 seconds, up to 50%[x].

      • +10.0% Resistance to All Elements
      • +10.0% Resistance to All Elements

      Affixes: (Item Power 925)
      4048803924.png

      Tyrael's Might

      "Thus Tyrael, a perfect aspect of Justice, came to be. None were more vehement against the forces of hell. All demonic entities learned to shudder at Justice's might." -The Books of Jarl, Volume I

      Type: Mythic Unique Chest Armor
      Class: All Classes

      Description: While at full Life, your Skills unleash a divine barrage dealing 195 damage.


        Affixes: (Item Power 925)
        • +11.2% Resistance to All Elements
        • +5.0% Maximum Resistance to All Elements
        • +18 All Stats
        • 10.0% Damage Reduction


        Uber Unique Crafting
        Uber Unique Crafting


        Alchemist Locations

        Alchemists are found in the following locations:

        Fractured Peaks

        • Kyovoshad, Desolate Highlands ([Map])

        Scosglen

        • Cerrigar, The Emerald Chase ([Map])

        Dry Steppes

        • Ked Bardu, Kotama Grasslands ([Map])

        Hawezar

        • Wejinhani, Dismal Foothills ([Map])
        • Zarbinet, Umir Plateau ([Map])

        Kehjistan

        • Gea Kul, Southern Expanse ([Map])


        Changes to Alchemist

        Patch 1.4.0, May 14, 2024

        Elixirs

        • Complete reworking of Elixirs with some removed, others combined and adding some new ones including rare.

        Resource Upgrades

        • Removed Gallowine, Blightshade, Biteberry, Lifesbane, Howler Moss and Reddamine. Replaced with Bundled Herbs that do not need upgrading.
        • Removed Silver Ore and Superior Leather.

        Transmute

        • Added Tyrael's Might
        • Reduced level requirement from 60 to 35