Diablo 4 Wiki Home Diablo 4 Guides Interactive Map Forums Diablo 2 Guides Support PureDiablo Discord

Elixir of Destruction II

From Diablo 4 Wiki

Elixir of Destruction II increases Overpower and Vulnerable damage as well as the rate at which you earn Experience Points. This is an upgraded version of Elixir of Destruction.

Elixirs are a great way to boost stats and increase the rate at which you earn experience points.

Many of them are crafted by an Alchemist and will require you to collect Crafting Materials out in the world from bushes and slaying monsters. They can also drop as rewards and some can be purchased from the Dark Citadel Vendor.

  • Can have 1 Elixir active at the same time
  • Most last 30 minutes and persist through death, some last 15 minutes
  • Most affect only you
  • Can consume Elixirs whilst Crowd Controlled
  • You can have Incense active at the same time
  • Buffs from both your Elixir and Incense can stack but the Experience buff from any Elixir you have active will only stack with the Experience buff from a single Incense.
  • Most can be traded with other players
  • Full list of Elixirs


Name Req Description Cost
Elixir of Destruction II 50 Increases Overpower damage by 15% and Vulnerable damage by 15%. Experience gained increased by 8%. 10 Bundled Herbs
10 Angelbreath
2,000 Gold

This is a more powerful version of Elixir of Destruction.


Changes to Elixir of Destruction II

Patch 1.4.0, April 14, 2024

Added to the game in Season 4.