Wiki Home Diablo 4 Guides Builds Build Planner Map Diablo 2 Guides Forums Support PureDiablo Vessel of Hatred

Poison Imbuement

From Diablo 4 Wiki

Poison Imbuement is a Rogue skill from the Imbuements skill tree. Its features are:

Grants Player Exploits Condition
Poison Dmg Critical Strike Chance *

'Creates Condition' means this skill creates this condition i.e it could make a target Vulnerable that other skills can take advantage of. 'Exploits Condition' means this skill takes advantage of a condition, not necessarily of its own making. So for example another skill might Stun and this skill could take advantage of that.

* An improved Critical Strike Chance for X seconds can be applied by non-imbueable skills but the increased Poison damage (from Blended Poison Imbuement) can only be exploited via a Poison Imbued Skill.


7199608.png

Poison Imbuement

Cooldown: 13 seconds
Lucky Hit Chance: 33%
Imbue your weapons with lethal poison. Your next 2 Imbueable Skills deal Poison damage and apply 100% of their Base damage as additional Poisoning damage over 6 seconds.

Damage: Poison
Tags: Imbuement, Imbueable
691022567.png

Alchemical Advantage

Dealing Poison damage increases your Attack Speed and Lucky Hit Chance by 1%[+] for 8 seconds, up to 5%[+] .

Prerequisite: Can also reach Alchemical Advantage via Poison Imbuement.

  • Poison Damage - initial hit with Poison and any Damage over Time (DoT) Poison
  • Poisoning Damage - only DoT Poison


Upgrades

Upgrade Hub
Enhanced Poison Imbuement

Casting Poison Imbuement generates 30 Energy, increased by 2 for each Nearby Poisoned enemy.

Upgrade Hub
Mixed Poison Imbuement

Lucky Hit: Poison Imbued Skills have up to a 30% chance to reduce the Cooldown of Poison Imbuement by 2 seconds.

Blended Poison Imbuement Upgrade

Blended Poison Imbuement

Critical Strikes with Poison Imbued Skills deal x75% increased Poisoning damage.


Other Skills that work with Poison Imbuement

The following skills either:

  • Create a condition Poison Imbuement can exploit
  • Exploit a condition Poison Imbuement creates
Basic Tree
2825736727.png

Heartseeker

Lucky Hit Chance: 50%
Fire an arrow that seeks an enemy, dealing 24% damage and increasing your Critical Strike Chance against them by 5%[+] for 4 seconds, up to 15%[+].

Damage: Physical Damage
Requires a Ranged weapon
Tags: Basic, Marksman, Chain Skill

Upgrade Hub
Fundamental Heartseeker

Heartseeker also increases the Critical Strike Damage the enemy takes by x 5% for 4 seconds, up to x 15%.

Skill

Core Tree
983874568.png

Twisting Blades

Energy Cost: 30
Lucky Hit Chance: 33%
Impale an enemy with your blades, dealing 70% damage and making them take 8%[x] increased damage from you for 1.5 seconds. After 1.5 seconds the blades return to you, piercing enemies for 86% damage.

Damage: Physical Damage
Requires Dual Wielded weapons
Tags: Core, Cutthroat, Imbueable Skill

2489669816.png

Barrage

Energy Cost: 30
Lucky Hit Chance: 16%
Unleash a barrage of 5 arrows that expands outwards, each dealing 22% damage. Each arrow has a 20% chance to ricochet off an enemy up to 1 time. Ricochets deal 40% of the arrow's Base damage.

Damage: Physical Damage
Requires a Ranged weapon
Tags: Core, Marksman, Imbueable, Chain Skill

Upgrade Hub
Enhanced Barrage

Barrage's ricochet chance is increased to 100% for arrows that damage a Vulnerable enemy or Critically Strike any enemy.

Skill

Advanced Barrage Upgrade

Advanced Barrage

Whenever a single cast of Barrage ricochets at least 4 times, your next cast gains 20%[+] increased Critical Strike Chance.

Skill

3328799720.png

Flurry

Energy Cost: 25
Lucky Hit Chance: 20%
Unleash a flurry of stabs and slashes, striking enemies in front of you 4 times and dealing a total of 150% damage to each.

Damage: Physical Damage
Requires Dual Wielded weapons
Tags: Core, Cutthroat, Imbueable Skill

353880186.png

Rapid Fire

Energy Cost: 25
Lucky Hit Chance: 20%
Rapidly fire 5 arrows, each dealing 40% damage.

Damage: Physical Damage
Requires a Ranged weapon
Tags: Core, Marksman, Imbueable, Chain Skill

Enhanced Rapid Fire Upgrade

Enhanced Rapid Fire

Each subsequent arrow from Rapid Fire has 7%[+] increased Critical Strike Chance, up to 25%[+] on the 5th arrow.

Skill

Advanced Rapid Fire Upgrade

Advanced Rapid Fire

Rapid Fire deals 30%[x] increased Critical Strike Damage for 5 seconds after you Evade.

Skill

3769175811.png

Penetrating Shot

Energy Cost: 35
Lucky Hit Chance: 50%
Fire an arrow that pierces through all enemies in a line, dealing 95% damage, increased by 10%[x] per enemy it pierces.

Damage: Physical Damage
Requires a Ranged weapon
Tags: Core, Marksman, Imbueable Skill

Upgrade Hub
Improved Penetrating Shot

Penetrating Shot has +10% Critical Strike Chance. If Penetrating Shot damages at least 3 enemies, you gain +10% increased Critical Strike Chance for 5 seconds.

Skill

Agility Tree
446244646.png

Shadow Step

Cooldown: 9 seconds
Lucky Hit Chance: 100%
Become Unstoppable and quickly move through the shadows to stab your victim from behind for 80% damage. Gain 50% increased Movement Speed for 2 seconds afterwards.

Damage: Physical Damage
Requires Dual Wielded weapons
Tags: Agility, Cutthroat, Imbueable, Mobility Skill

Enhanced Shadow Step Upgrade

Enhanced Shadow Step

Damaging an enemy with Shadow Step Dazes and applies Vulnerable to them for 3 seconds.

Skill

1561866532.png

Dash

Charges: 2
Charge Cooldown: 12 seconds
Lucky Hit Chance: 25%
Dash forward and slash enemies for 65% damage. Any enemies hit are Slowed (CC) by 30% for 3 seconds.

Damage: Physical Damage
Requires Dual Wielded weapons
Tags: Agility, Cutthroat, Imbueable, Mobility Skill

Disciplined Caltrops Upgrade

Disciplined Caltrops

You have +10% Critical Strike Chance against enemies inside your Caltrops. Double this amount against Vulnerable enemies.

Skill

3204755432.png

Weapon Mastery

Gain a bonus when attacking based on weapon type used in your attack:
Daggers: 7%[x] increased damage to Healthy and Injured enemies.
Swords: 3%[x] increased damage.
Bows: 4%[x] increased damage to Vulnerable enemies.
Crossbows: 5%[x] increased Critical Strike Damage. Passive

715330267.png

Unstable Elixirs

Using a Healing Potion Stuns (CC) surrounding enemies for 2 seconds and increases your damage by 6% for 10 seconds. You may now drink your Healing Potion while at full health.

Passive

Subterfuge
Upgrade Hub
Countering Dark Shroud

While you have at least 2 active shadow from Dark Shroud, gain +8% Critical Strike Chance.

Skill

Upgrade Hub
Subverting Poison Trap

You deal x10% increased Poisoning Damage to enemies standing inside your Poison Trap.

Skill

Countering Poison Trap Upgrade

Countering Poison Trap

Poison Trap has a 40% chance to reset your Imbuement Skill Cooldowns when activated.

Skill

Upgrade Hub
Countering Concealment

Casting Concealment grants 10% Dodge Chance, increases the Movement Speed bonus to 60%[+], and gives all of its other bonuses for the full 5 seconds. Skill

Imbuements
Enhanced Shadow Imbuement Upgrade

Enhanced Shadow Imbuement

You have +15% increased Critical Strike Chance against Injured enemies infected by Shadow Imbuement .

Skill

Upgrade Hub
Mixed Shadow Imbuement

Enemies infected by Shadow Imbuement take x12% increased Non-Physical damage for 8 seconds.

Skill

3147175262.png

Precision Imbuement

Imbued Skills gain 3%[+] increased Critical Strike Chance. Passive

1573888709.png

Deadly Venom

You deal 6%[x] increased Poisoning damage. Passive

691022567.png

Alchemical Advantage

Dealing Poison damage increases your Attack Speed and Lucky Hit Chance by 1%[+] for 8 seconds, up to 5%[+] .

Prerequisite: Can also reach Alchemical Advantage via Poison Imbuement. Passive

1143413012.png

Debilitating Toxins

Poisoned enemies deal 5% less damage. Passive

Ultimate Tree
914686433.png

Rain of Arrows

Cooldown: 50 seconds
Lucky Hit Chance: 12%
Arrows rain down over a large area dealing 450% damage and Knocking Down enemies for 3 seconds.

Damage: Physical Damage
Requires a Ranged weapon
Tags: Ultimate, Marksman, Imbueable Skill

Upgrade Hub
Prime Rain of Arrows

Imbuement Skill effects applied by Rain of Arrows have x50% increased potency.

Skill

1934010081.png

Alchemist's Fortune

Non-Physical damage you deal has a 5%[+] increased Lucky Hit Chance.

Damage: Physical Damage
Passive


Items that work with Poison Imbuement

The following items either:

  • Grant a bonus when using Poison Imbuement
  • Create a condition Poison Imbuement can exploit
  • Exploit a condition Poison Imbuement creates

Legendary Aspects

Aspect of Bursting Venoms
Offensive Lucky Hit:Poison Imbued Skills have up to a 15% chance to create a toxic pool that deals 420 - 546 Poisoning damage over 3 seconds (DoT) to enemies within.

While standing in the pool, your Poison Imbuement Skill has no Cooldown and no Charge limit.


Gloves, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%)
N/A Extraction Rogue
Aspect of Corruption
Offensive Your Imbuement Skill effects have 25 - 45% [x] increased potency against Vulnerable enemies.

Gloves, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%)
Renegade's Retreat
(Map)
Kehjistan Rogue
Aspect of Imitated Imbuement
Offensive Your Shadow Clones also mimic the Imbuements applied to your Skills. Casting an Imbuement Skill grants your active Shadow Clone 5 - 25% [x] increased damage for 9 seconds.

Gloves, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%)
N/A Extraction Rogue
Aspect of Noxious Ice
Utility Chilled enemies Poisoned by Poison Imbuement will be further Chilled for 20% per second. You deal 20 - 40% [x] additional Poison damage to Frozen (CC) enemies.

Helm, Chest, Pants, Gloves, Boots, Amulet (+50%)
N/A Extraction Rogue
Aspect of Unstable Imbuements
Offensive When casting an Imbuement Skill you trigger an explosion around yourself, applying the Imbuement effects and dealing 83 - 175 damage of the same type.

Gloves, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%)
Whispering Vault
(Map)
Dry Steppes Rogue
Toxic Alchemist's Aspect
Offensive Lucky Hit: Shadow Imbued Skills have up to a 75% chance to create a toxic explosion that applies 60 - 90 Poisoning damage over 5 seconds to the target and surrounding enemies. If they were already Poisoned, increase this damage by x100%.

Gloves, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%)
N/A Extraction Rogue
Vengeful Aspect
Offensive Lucky Hit: Damaging a Vulnerable enemy has up to a 25% chance to create an Arrow Storm at the enemy's location, dealing 156 - 486 Physical damage over 3 seconds.

Your Arrow Storms deal 156 - 486% increased damage.


Gloves, 1H Weapon, 2H Weapon (+100%), Ring, Amulet (+50%)
Inferno
(Map)
Kehjistan Rogue

* Extraction means the Legendary Aspect can be removed from any Legendary item at the Occultist. A dungeon name means the Aspect will be added to your Codex of Power as a reward after completing that dungeon.

Unique Items

There are no unique items that exploit Poison Imbuement.


Changes to Poison Imbuement

  • Mixed Poison Imbuement
    • Previous: Lucky Hit: Poison Imbued skills have up to a 30% chance to apply double the amount of Poisoning damage over time.
    • New: Lucky Hit: Poison Imbued skills have up to a 30% chance to reduce Poison Imbuement’s cooldown by 2 seconds.