Runes are small objects that, like gems and jewels, have no function until they are socketed into an item. How to use a Rune Runes add different properties to shields or armor vs. weapons, and sometimes shields and armor differ as well. See the full runes listing here. Runes can be upgraded; 2 or 3 of one type, plus a particular gem type/quality, can be combined in the Horadric Cube to upgrade to the next higher level rune. Runes are most powerful when combined into special runewords, so be sure you…

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Diablo 4 Runes

Diablo 4 Runes and Runewords

An updated list of all the Diablo IV known runes and runwords.

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