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From Diablo 4 Wiki

Crafting is a feature of Diablo 4 and there are numerous different crafting materials in the game.

Crafting materials include plants, skins, salvaged materials, monster parts.

Where to use Crafting Materials

These vendors can be found in major towns and also In Strongholds once they have been liberated.

Where to find the Crafting Materials

Crafting materials come from a variety of locations, creatures, ore veins, drop rewards in chests, world bosses, and enemies.

A full lost of crafting materials and their location can be found on the Crafting Materials page.