My barb wears CoH in a sacred armour. 232 str req is steep, but if you can afford CoH you can probably afford other items to make up for investing so heavily in strength. I don't know about PvP, but PvM it is absolutely wonderful: it does everything (1000 def, leech, damage reduction, extra damage, resists, mf, skills...).
Maybe it is a great armour for a pit running bowazon.
1. Everything is either a demon or undead
2. (Pit) Bowazons tend to have very poor resists. This would help out, somewhat (with just 3 Anya quests you make it back to about 0!). The unique critters with elemental mods wouldn't be so worrying (and in the pit the only real worry is an annoying boss or two).
Also a good armour for builds that don't use a shield (shapeshifting Druids, perhaps).